What Is PrEP for HIV Prevention?

PrEP (Pre-Exposure Prophylaxis) is a daily medication that prevents HIV infection. When taken as prescribed, it is more than 99% effective.

Medications

• Truvada: tenofovir/emtricitabine (approved for all at-risk populations)
• Descovy: tenofovir alafenamide/emtricitabine (not approved for vaginal sex)
• Apretude: long-acting injection every 2 months

Who Should Consider PrEP

• HIV-negative partner of HIV-positive person
• Multiple sexual partners without consistent condom use
• Recent bacterial STD
• Injecting drug use with sharing

Requirements

• Confirmed HIV-negative before starting
• HIV testing every 3 months while on PrEP
• Kidney function monitoring
• Adherence is critical for effectiveness

Access

• Covered by most insurance
• Patient assistance programs available (Gilead Advancing Access)