What Is an Estradiol Blood Test?

Estradiol (E2) is the primary female sex hormone produced by the ovaries.

Normal Ranges

• Follicular phase: 19–144 pg/mL
• Ovulation: 64–357 pg/mL
• Luteal phase: 56–214 pg/mL
• Postmenopausal: below 10 pg/mL
• Men: 10–50 pg/mL

When Tested

• Fertility evaluation
• IVF monitoring
• Menopause confirmation
• Hormone therapy monitoring
• PCOS evaluation

High Estradiol

• PCOS
• Ovarian tumors
• Estrogen therapy
• Obesity (aromatization)

Low Estradiol

• Menopause
• Premature ovarian failure
• Excessive exercise
• Hypothalamic amenorrhea