What Medications Cause a False Positive Drug Test?
Several medications and foods can cause false positive screening results.
Known Cross-Reactions
- Poppy seeds → opiates
- Pseudoephedrine → amphetamines
- Levofloxacin → cocaine
- Sertraline → benzodiazepines
- Dextromethorphan → PCP
Why They Happen
- Immunoassays detect drug classes, not specific drugs
- Similar molecular structure cross-reacts
How Resolved
- GC-MS confirmation identifies exact substance
- Inform lab if taking cross-reacting medication
Source: SAMHSA, NIDA, Mayo Clinic.
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