What Is Metabolic Syndrome?

Metabolic syndrome is a cluster of conditions that together increase risk of heart disease, stroke, and diabetes.

Diagnostic Criteria (3+ of 5)

  • 1. Waist circumference: above 40" (men) or 35" (women)
  • 2. Triglycerides: 150 mg/dL or above
  • 3. HDL: below 40 (men) or 50 (women)
  • 4. Blood pressure: 130/85 or above
  • 5. Fasting glucose: 100 mg/dL or above

Prevalence

  • 35% of U.S. adults
  • 50% of people over 60

Health Risks

  • 2× risk of cardiovascular disease
  • 5× risk of type 2 diabetes
  • Increased risk of fatty liver

Treatment

  • Weight loss (5–10% of body weight)
  • Exercise
  • Diet (Mediterranean or low-carb)
  • Address each component individually
Source: American Diabetes Association, AACC.

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