What Are Neutrophils in a Blood Test?

Neutrophils are the most abundant white blood cell (40–60% of WBC). They are your immune system's first responders against bacterial infections.

Normal Range

  • Absolute: 2,500–7,000/µL
  • Percentage: 40–60%

High Neutrophils (Neutrophilia)

  • Bacterial infection — most common cause
  • Physical stress — exercise, surgery, trauma
  • Inflammation
  • Smoking
  • Corticosteroids
  • Myeloproliferative disorders

Low Neutrophils (Neutropenia)

  • Chemotherapy — most common cause in cancer patients
  • Viral infection
  • Autoimmune disease
  • Certain medications
  • B12 or folate deficiency
  • Severe malnutrition

Severity of Neutropenia

  • Mild: 1,000–1,500/µL
  • Moderate: 500–1,000/µL
  • Severe: below 500/µL — high infection risk, febrile neutropenia is an emergency

Left Shift

  • Increased immature neutrophils (bands) = active bacterial infection, bone marrow releasing stored cells
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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