What Are Monocytes in a Blood Test?

Monocytes are white blood cells that circulate in the blood and become macrophages in tissues, engulfing debris and pathogens.

Normal Range

  • 2–8% of WBC
  • Absolute: 200–800/µL

High Monocytes (Monocytosis)

  • Chronic infection (tuberculosis, endocarditis)
  • Recovery phase after acute infection
  • Autoimmune disease
  • Inflammatory bowel disease
  • Leukemia (rare)

Low Monocytes

  • Usually not clinically significant
  • Bone marrow suppression
  • Corticosteroid use
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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