What Is an Iron Blood Test?

An iron blood test typically refers to an iron panel — multiple tests interpreted together.

Serum Iron

  • Iron circulating in blood bound to transferrin
  • Normal: 60–170 µg/dL (men), 30–160 µg/dL (women)
  • Fluctuates throughout the day — not reliable alone

TIBC

  • How much transferrin is available to bind iron
  • Normal: 240–450 µg/dL
  • High = iron deficiency
  • Low = iron overload or inflammation

Transferrin Saturation

  • (Serum Iron ÷ TIBC) × 100
  • Normal: 20–50%
  • Below 20% = iron deficiency
  • Above 45% = iron overload (hemochromatosis)

Ferritin

  • Stored iron — most reliable single marker
  • Normal: 20–500 (men), 20–200 (women) ng/mL

Interpreting Together

  • Iron deficiency: low ferritin + high TIBC + low saturation
  • Iron overload: high ferritin + low TIBC + high saturation
  • Chronic disease anemia: normal/high ferritin + low TIBC + low iron
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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