What Is HbA1c in a Blood Test?

HbA1c (glycated hemoglobin) measures the percentage of hemoglobin with glucose attached. Reflects average glucose over 2–3 months.

Reference Ranges

  • Normal: below 5.7%
  • Prediabetes: 5.7–6.4%
  • Diabetes: 6.5%+
  • Goal for diabetics: below 7.0%
  • HbA1c 7% ≈ avg glucose 154 mg/dL
  • HbA1c 9% ≈ avg glucose 212 mg/dL

Why HbA1c Is the Gold Standard

  • No fasting required
  • Not affected by recent meals or stress
  • Correlates with complication risk
  • Standardized and reliable

Limitations

  • Anemia — can falsely alter HbA1c
  • Hemoglobinopathies — sickle cell, thalassemia
  • Pregnancy — less reliable
  • Kidney disease

Testing Frequency

  • Screening: every 3 years from age 35
  • Prediabetes: annually
  • Diabetes (stable): every 6 months
  • Diabetes (uncontrolled): every 3 months
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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