What Is Ferritin in a Blood Test?

Ferritin is the protein that stores iron inside your cells. It is the best single marker of your body's total iron stores.

Normal Ranges

  • Men: 20–500 ng/mL
  • Women: 20–200 ng/mL
  • Optimal functional range: 50–150 ng/mL
  • Below 20 = iron deficiency (even before anemia)
  • Below 12 = depleted iron stores

Low Ferritin Causes

  • Inadequate dietary iron — vegetarian/vegan diets
  • Chronic blood loss — heavy menstruation, GI bleeding
  • Malabsorption — celiac disease, gastric bypass
  • Increased demand — pregnancy, growth
  • Endurance exercise

High Ferritin Causes

  • Inflammation — ferritin is an acute-phase reactant
  • Hemochromatosis — genetic iron overload
  • Liver disease
  • Alcohol use
  • Metabolic syndrome
  • Blood transfusions

Important Caveat

  • Ferritin rises with inflammation even when iron stores are low
  • Check CRP and transferrin saturation if inflammation is suspected
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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