What Is Creatine Kinase (CK) in a Blood Test?

CK is found in heart, skeletal muscle, and brain. It rises when muscle tissue is damaged.

Normal Range

  • 30–200 U/L
  • Higher in muscular individuals

Elevated CK Causes

  • Intense exercise — most common
  • Muscle injury or trauma
  • Rhabdomyolysis — severe (emergency)
  • Heart attack (CK-MB fraction)
  • Statins
  • Hypothyroidism

Rhabdomyolysis Warning

  • CK above 5,000 = emergency
  • Can cause kidney failure
  • Dark urine + severe muscle pain = urgent
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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