What Is Total Bilirubin in a Blood Test?

Total bilirubin measures the yellow pigment produced when red blood cells break down.

Normal Range

  • 0.3–1.2 mg/dL
  • Above 2.5 = jaundice visible

High Bilirubin Causes

  • Hemolysis (red cell destruction)
  • Gilbert syndrome (benign)
  • Liver disease
  • Bile duct obstruction

Direct vs Indirect

  • Indirect high: hemolysis or Gilbert
  • Direct high: obstruction or liver disease
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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