What Is a Reticulocyte Count?

Reticulocytes are newly produced red blood cells that still contain RNA. They mature into fully functional RBCs within 1–2 days.

Normal Range

  • 0.5–2.5% of RBCs
  • Absolute: 25,000–75,000/µL

High Reticulocytes

  • Blood loss (marrow compensating)
  • Hemolytic anemia (marrow replacing destroyed cells)
  • After iron/B12/folate treatment (response)

Low Reticulocytes

  • Bone marrow failure
  • Aplastic anemia
  • Chemotherapy
  • Nutritional deficiency (untreated)
  • Kidney disease (low EPO)
Source: NLM MedlinePlus, American Association for Clinical Chemistry.

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