What Does High MCHC Mean?
High MCHC means red blood cells are more concentrated with hemoglobin than normal. This is uncommon.
Causes
- Hereditary spherocytosis — genetic condition
- Severe burns — red cells lose water
- Autoimmune hemolytic anemia
- Cold agglutinin disease
- Lab artifact (often the cause)
Next Steps
- Verify with repeat CBC
- Blood smear examination
- Hemolysis markers if suspected
Source: NLM MedlinePlus, American Association for Clinical Chemistry.
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