What Does High MCHC Mean?

High MCHC means red blood cells are more concentrated with hemoglobin than normal. This is uncommon.

Causes

• Hereditary spherocytosis — genetic condition
• Severe burns — red cells lose water
• Autoimmune hemolytic anemia
• Cold agglutinin disease
• Lab artifact (often the cause)

Next Steps

• Verify with repeat CBC
• Blood smear examination
• Hemolysis markers if suspected