Venlafaxine: Side Effects, Uses & Monitoring
Facts extracted from current FDA product labeling for Venlafaxine. Educational only — not medical advice.
Reported adverse reactions
| Reaction | Highest frequency reported* |
|---|---|
| Abnormal ejaculation | 16% |
| Nausea | 8% |
| Constipation | 8% |
| Diarrhea | 8% |
| Pharyngitis | 7% |
| Dyspepsia | 7% |
| Abdominal pain | 6% |
| Anxiety | 5% |
| Hypertension | 4% |
| Flatulence | 4% |
| Accidental injury | 4% |
| Asthenia | 3% |
| Insomnia | 3% |
| Somnolence | 3% |
| Weight loss | 3% |
| Depression | 3% |
| Paresthesia | 3% |
| Libido decreased | 3% |
| Agitation | 3% |
| Yawn | 3% |
*Highest percentage across placebo-controlled trial tables summarized in current labeling.
Labeled uses
Major Depressive Disorder Venlafaxine hydrochloride extended-release capsules are indicated for the treatment of major depressive disorder. The efficacy of venlafaxine hydrochloride extended-release capsules in the treatment of major depressive disorder was established in 8- and 12-week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III-R or DSM-IV category of major depressive disorder (see Clinical Trials ). A major depressive episode (DSM-IV) implies a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed mood or the loss of interest or pleasure in nearly all activities, representing a change from previous functioning, and includes the presence of at least five of the following nine symptoms during the same two-week period: depressed mood, markedly diminished interest or pleasure in usual activities, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, a suicide attempt or suicidal ideation. The efficacy of venlafaxine hydrochloride tablets (immediate r…
Medical disclaimer: Always consult a qualified healthcare professional about any medication.