Tizanidine: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Tizanidine. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Asthenia *78%
Dry mouth49%
Somnolence48%
Asthenia*41%
Hypotension33%
Dizziness16%
Uti10%
Bradycardia10%
Infection6%
Constipation4%
Liver function tests abnormal3%
Vomiting3%
Speech disorder3%
Amblyopia (blurred vision)3%
Urinary frequency3%
Flu symptom3%
Sgpt/alt increased3%
Dyskinesia3%
Nervousness3%
Pharyngitis3%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

Tizanidine tablets are a short-acting drug for the management of spasticity. Because of the short duration of effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important (see DOSAGE AND ADMINISTRATION ).

Source: FDA labeling via NIH DailyMed (set 5a42267f…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.