Testosterone: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Testosterone. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Application site reactions4%
Hematocrit/hemoglobin increased2%
Benign prostatic hyperplasia1%
Blood pressure diastolic decreased1%
Blood pressure increased1%
Gynecomastia1%
Headache1%
Hot flushes1%
Insomnia1%
Lacrimation increased1%
Mood swings1%
Smell disorder1%
Spontaneous penile erection1%
Taste disorder1%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

INDICATIONS AND USAGETestim® is indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone: Primary hypogonadism (congenital or acquired): testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter's syndrome, chemotherapy, or toxic damage from alcohol or heavy metals. These men usually have low serum testosterone levels and gonadotropins (FSH, LH) above the normal range. Hypogonadotropic hypogonadism (congenital or acquired): idiopathic gonadotropin or luteinizing hormone-releasing hormone (LHRH) deficiency or pituitary-hypothalamic injury from tumors, trauma, or radiation. These men have low testosterone serum levels but have gonadotropins in the normal or low range. Testim® has not been clinically evaluated in males under 18 years of age.

Source: FDA labeling via NIH DailyMed (set 0d90cadf…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.