Progesterone: Side Effects, Uses & Monitoring
Facts extracted from current FDA product labeling for Progesterone. Educational only — not medical advice.
Reported adverse reactions
| Reaction | Highest frequency reported* |
|---|---|
| Hot flashes | 35% |
| Headache | 31% |
| Joint pain | 29% |
| Breast tenderness | 27% |
| Depression | 19% |
| Night sweats | 17% |
| Dizziness | 15% |
| Abdominal pain | 13% |
| Abdominal bloating | 12% |
| Pain | 12% |
| Infection viral | 12% |
| Urinary problems | 11% |
| Vaginal discharge | 10% |
| Vaginal dryness | 10% |
| Feet | 9% |
| Nausea / vomiting | 8% |
| Worry | 8% |
| Fatigue | 8% |
| Nausea | 8% |
| Back pain | 8% |
*Highest percentage across placebo-controlled trial tables summarized in current labeling.
Labeled uses
PROMETRIUM Capsules are indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea.
Source: FDA labeling via NIH DailyMed (set cf73c385…). Not affiliated with FDA or NIH.
Medical disclaimer: Always consult a qualified healthcare professional about any medication.