Nicardipine: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Nicardipine. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Pedal edema7.1%
Dizziness6.9%
Headache6.4%
Asthenia5.8%
Flushing5.6%
Increased angina5.6%
Palpitations3.3%
Nausea1.9%
Dyspepsia1.5%
Dry mouth1.4%
Somnolence1.4%
Rash1.2%
Tachycardia1.2%
Myalgia1%
Other edema1%
Paresthesia1%
Sustained tachycardia0.8%
Syncope0.8%
Constipation0.6%
Dyspnea0.6%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

I. Stable Angina Nicardipine hydrochloride capsules are indicated for the management of patients with chronic stable angina (effort-associated angina). Nicardipine hydrochloride capsules may be used alone or in combination with beta-blockers. II. Hypertension Nicardipine hydrochloride capsules are indicated for the treatment of hypertension. Nicardipine hydrochloride capsules may be used alone or in combination with other antihypertensive drugs. In administering nicardipine hydrochloride it is important to be aware of the relatively large peak to trough differences in blood pressure effect (See DOSAGE AND ADMINISTRATION ).

Source: FDA labeling via NIH DailyMed (set edda985c…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.