Nalmefene: Side Effects, Uses & Monitoring
Facts extracted from current FDA product labeling for Nalmefene. Educational only — not medical advice.
Reported adverse reactions
| Reaction | Highest frequency reported* |
|---|---|
| Nausea | 18% |
| Vomiting | 9% |
| Tachycardia | 8% |
| Hypertension | 7% |
| Postoperative pain | 4% |
| Fever | 4% |
| Dizziness | 4% |
| Headache | 4% |
| Chills | 1% |
| Hypotension | 1% |
| Vasodilation | 1% |
*Highest percentage across placebo-controlled trial tables summarized in current labeling.
Labeled uses
Nalmefene hydrochloride injection is indicated for the complete or partial reversal of opioid drug effects, including respiratory depression, induced by either natural or synthetic opioids. Nalmefene hydrochloride injection is indicated in the management of known or suspected opioid overdose.
Source: FDA labeling via NIH DailyMed (set 3abfbffc…). Not affiliated with FDA or NIH.
Medical disclaimer: Always consult a qualified healthcare professional about any medication.