Megestrol: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Megestrol. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Mg/day1200%
Diarrhea15%
Impotence14%
Rash12%
Flatulence10%
Headache10%
Nausea9%
Vomiting9%
Hypertension8%
Asthenia8%
Insomnia6%
Anemia6%
Fever6%
Hyperglycemia6%
Pain6%
Pneumonia6%
Libido decreased5%
Dyspepsia5%
Urinary frequency5%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

INDICATIONS AND USAGE Megace ® ES (megestrol acetate) oral suspension is indicated for the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS).

Source: FDA labeling via NIH DailyMed (set 33bc102c…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.