Doxazosin: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Doxazosin. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Dizziness19%
Fatigue/malaise12%
Headache9.9%
Dizziness†9%
Somnolence3%
Rhinitis3%
Abdominal pain2.4%
Diarrhea2.3%
Urinary tract infection2.3%
Back pain2%
Pain2%
Vertigo2%
Nervousness2%
Sexual dysfunction2%
Polyuria2%
Micturition frequency2%
Fatigue1.7%
Dyspepsia1.7%
Nausea1.5%
Mouth dry1.4%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

Benign Prostatic Hyperplasia (BPH)Doxazosin tablets are indicated for the treatment of both the urinary outflow obstruction and obstructive and irritative symptoms associated with BPH: obstructive symptoms (hesitation, intermittency, dribbling, weak urinary stream, incomplete emptying of the bladder) and irritative symptoms (nocturia, daytime frequency, urgency, burning). Doxazosin may be used in all BPH patients whether hypertensive or normotensive. In patients with hypertension and BPH, both conditions were effectively treated with doxazosin monotherapy. Doxazosin provides rapid improvement in symptoms and urinary flow rate in 66 to 71% of patients. Sustained improvements with doxazosin were seen in patients treated for up to 14 weeks in double-blind studies and up to 2 years in open-label studies. HypertensionDoxazosin tablets are also indicated for the treatment of hypertension. Doxazosin may be used alone or in combination with diuretics, beta-adrenergic blocking agents, calcium channel blockers or angiotensin-converting enzyme inhibitors.

Source: FDA labeling via NIH DailyMed (set 05e29a60…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.