Clonazepam: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Clonazepam. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Somnolence †50%
Tract infection †10%
Coordination abnormal †9%
Fatigue9%
Ataxia †8%
Sinusitis8%
Somnolence7%
Dysmenorrhea6%
Coordination abnormal6%
Memory disturbance5%
Constipation †5%
Influenza5%
Depression4%
Dysarthria †4%
Rhinitis4%
Coughing4%
Allergic reaction4%
Myalgia4%
Colpitis4%
Libido decreased3%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

INDICATIONS AND USAGE Seizure Disorders: Clonazepam is useful alone or as an adjunct in the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic, and myoclonic seizures. In patients with absence seizures (petit mal) who have failed to respond to succinimides, clonazepam may be useful. Some loss of effect may occur during the course of clonazepam treatment (see PRECAUTIONS : Loss of Effect). Panic Disorder: Clonazepam is indicated for the treatment of panic disorder, with or without agoraphobia, as defined in DSM-V. Panic disorder is characterized by the occurrence of unexpected panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and/or a significant change in behavior related to the attacks. The efficacy of clonazepam was established in two 6- to 9-week trials in panic disorder patients whose diagnoses corresponded to the DSM-IIIR category of panic disorder (see CLINICAL PHARMACOLOGY: CLINICAL TRIALS). Panic disorder (DSM-V) is characterized by recurrent unexpected panic attacks, i.e., a discrete period of intense fear or discomfort in which four (or more) of the following symptoms deve…

Source: FDA labeling via NIH DailyMed (set be383e56…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.