Chlorhexidine: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Chlorhexidine. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Toothache*114%
Upper resp tract infection64%
Headache61%
Sinusitis31%
Influenza-like symptoms17%
Back pain15%
Tooth disorder**14%
Bronchitis14%
Abscess13%
Pain11%
Allergy9%
Myalgia9%
Gum hyperplasia8%
Pharyngitis8%
Arthralgia7%
Dysmenorrhea7%
Dyspepsia7%
Rhinitis6%
Coughing6%
Arthrosis6%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

PerioChip is indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. PerioChip may be used as a part of a periodontal maintenance program, which includes good oral hygiene and scaling and root planing.

Source: FDA labeling via NIH DailyMed (set c40ab6ac…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.