Cefazolin: Side Effects, Uses & Monitoring
Facts extracted from current FDA product labeling for Cefazolin. Educational only — not medical advice.
Reported adverse reactions
| Reaction | Highest frequency reported* |
|---|---|
| 190 mg | 50% |
| 375 mg | 50% |
| 150 mg | 40% |
| 300 mg | 40% |
| 115 mg | 30% |
| 225 mg | 30% |
| 75 mg | 20% |
| 40 mg | 10% |
*Highest percentage across placebo-controlled trial tables summarized in current labeling.
Labeled uses
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection, USP and other antibacterial drugs, Cefazolin for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Cefazolin for injection, USP is indicated in the treatment of the following serious infections due to susceptible organisms: RESPIRATORY TRACT INFECTIONS due to Streptococcus pneumoniae, Klebsiella species, Haemophilus influenzae, Staphylococcus aureus (penicillin-sensitive and penicillin-resistant) and group A beta-hemolytic streptococci. Injectable benzathine penicillin is considered to be the drug of choice in treatment and prevention of streptococcal infections including the prophylaxis of rheumatic fever. Cefazolin is effective in the eradication of streptococci from the nasopharynx; however, data establishing the efficacy…
Medical disclaimer: Always consult a qualified healthcare professional about any medication.