Carbidopa: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Carbidopa. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Dyskinesia16.5%
Nausea5.7%
Hallucinations3.9%
Confusion3.7%
Dizziness2.9%
Urinary tract infection2.3%
Depression2.2%
Headache2%
Vomiting1.9%
Dream abnormalities1.8%
Dystonia1.8%
Upper respiratory infection1.8%
Dyspnea1.6%
“on-off” phenomena1.6%
Back pain1.6%
Constipation1.5%
Dry mouth1.4%
Anorexia1.2%
Diarrhea1.2%
Insomnia1.2%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

Carbidopa and levodopa extended release tablets are indicated in the treatment of the symptoms of idiopathic Parkinson’s disease (paralysis agitans), postencephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication.

Source: FDA labeling via NIH DailyMed (set abff005f…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.