Calfactant: Side Effects, Uses & Monitoring

Facts extracted from current FDA product labeling for Calfactant. Educational only — not medical advice.

Reported adverse reactions

ReactionHighest frequency reported*
Apnea61%
Patent ductus arteriosus48%
Intracranial hemorrhage31%
Sepsis22%
Pulmonary air leaks22%
Pulmonary interstitial emphysema17%
Pulmonary hemorrhage7%
Necrotizing enterocolitis5%

*Highest percentage across placebo-controlled trial tables summarized in current labeling.

Labeled uses

INFASURF is indicated: to reduce the risk of respiratory distress syndrome (RDS) in preterm neonates <29 weeks of gestational age at risk for RDS. for the rescue treatment of RDS in preterm neonates ≤72 hours of age with RDS who require endotracheal intubation.

Source: FDA labeling via NIH DailyMed (set 315c128a…). Not affiliated with FDA or NIH.

Medical disclaimer: Always consult a qualified healthcare professional about any medication.